:+:JGO-Journal Of Gynecologic Oncology:+:

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December 2008, Vol. 19 No. 4

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Published online 2008 Dec;19(4):218-222

Gynecologic oncology group trials in uterine corpus malignancies: recent progress

David Scott Miller¹, Louise P. King²

¹Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, ²Resident in Obstetrics and Gynecology, Parkland Memorial Hospital, University of Texas Southwestern Medical Center, Dallas, TX, USA

Abstract

The Gynecologic Oncology Group (GOG) has conducted multiple trials related to malignancies of the uterine corpus. Recently, several of these trials have been presented and/or published. Areas of focus included the feasibility of laparoscopic staging for endometrial cancer, the adjuvant management of locally advanced endometrial cancer, whole abdominal irradiation in maximally resected advanced endometrial carcinoma, and combination chemotherapy regimens for stage I and II carcinosarcoma after primary surgery and for advanced or recurrent carcinosarcoma. This article will discuss the background and details of each of these important advances.

Keywords : Endometrial neoplasm, Carcinosarcoma, Clinical trial