:+:JGO-Journal Of Gynecologic Oncology:+:

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July 2012, Vol. 23 No. 3

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Jae-Weon Kim, MD, PhD

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Published online 2012 Jul;23(3):201-204

Successful term pregnancies after laparoscopic excision of poorly differentiated Sertoli-Leydig cell tumor of the ovary

Vaidyanathan Gowri, Sreedharan V Koliyadan, Aisha Al Hamdani, Nayil Al Kindy

Departments of Obstetrics and Gynecology, Surgery, andPathology, Sultan Qaboos University Hospital, Sultan Qaboos University College of Medicine, Muscat, Sultanate of Oman

Abstract

Ovarian Sertoli-Leydig cell tumors are rare sex cord-stromal tumors, accounting for less than 1% of ovarian tumors. Majority of these tumors are benign and unilateral, only 3-5% are bilateral. These patients present with clinical features of virilization due to excessive secretion of testosterone from the tumor, however 50% may have no endocrine symptoms. We report a case of poorly differentiated Sertoli-Leydig cell tumour in a woman diagnosed during routine investigation of infertility. She had two spontaneous successful pregnancies after tumor excision laparoscopically.

Keywords : Laparoscopy, Malignancy, Pregnancy, Sex-cord stromal tumor